Reaction #433633
ord-17a7465a1e4348db8c123b7186989223
Reaction equation
7-(3-fluoro-benzyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine hydrochloride
methyl chloroformate
→
title compound
Yield 95.0%
7-(3-Fluoro-benzyloxy)-1,2,4,5-tetrahydro-benzo[d]azepine-3-carboxylic Acid Methyl Ester
Yield 95.0%
Reactants
Reagents
None
Solvents
Conditions
Detailed conditions
See reaction.notes.procedure_details.
Procedure
The title compound was prepared in analogy to Example 1d) from 7-(3-fluoro-benzyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine hydrochloride [Example 1c)] and methyl chloroformate with triethylamine as the base. Yield: 95% of theory as a colourless oil; MS: m/e=330 (M+H)+.