Reaction #433586

Reaction equation

Guanidine hydrochloride

hexamethylene diamine

→

polyhexamethyleneguanidine

Solvents

1,5-pentanediol

1,5-pentanediol

Conditions

Workup

1. 1
   TemperatureThe temperature of the reaction mixture was then raised to 150–170° C. for a further 10 hours
2. 2
   Temperaturewas maintained at 80° C. until dissolution
3. 3
   TemperatureThe mixture was then cooled

Procedure

Guanidine hydrochloride (200 parts) and hexamethylene diamine (292 parts) were heated to 120° C. for 4 hours under a nitrogen atmosphere. The temperature of the reaction mixture was then raised to 150–170° C. for a further 10 hours. The product was cooled to 80° C. and 1,5-pentanediol (400 parts) was added while the temperature was maintained at 80° C. until dissolution occurred. The mixture was then cooled to give a solution of polyhexamethyleneguanidine (prepolymer 3) in 1,5-pentanediol.

Source