Reaction #433584

Reaction equation

guanidine hydrochloride

hexamethylene diamine

→

polyhexamethyleneguanidine

Solvents

water

water

Conditions

Workup

1. 1
   Temperaturewas then raised to 150–170° C. for a further 5 hours
2. 2
   TemperatureThe mixture was cooled to 80° C.
3. 3
   Temperaturemaintaining the temperature at 80° C.
4. 4
   workup.DISSOLUTIONuntil dissolution
5. 5
   TemperatureThe mixture was then cooled

Procedure

A mixture of guanidine hydrochloride (200 parts) and hexamethylene diamine (292 parts) were heated to 120° C. for 4 hours under a nitrogen atmosphere The temperature was then raised to 150–170° C. for a further 5 hours. The mixture was cooled to 80° C. and water (400 parts) was added, maintaining the temperature at 80° C. until dissolution occurred. The mixture was then cooled to give a solution in water of polyhexamethyleneguanidine, referred to as Prepolymer 1, having a weight average molecular weight (Mw) of 1010 and a number average molecular weight (Mn) of 710, as determined by aqueous gel permeation chromatography.

Source