Reaction #41957

Reaction equation

Chloroacetaldehyde diethyl acetal

benzoic acid

potassium iodide

potassium carbonate

→

compound

Yield 56.0%

2-benzoyloxyacetaldehyde Diethyl Acetal

Yield 56.0%

Solvents

DMF

ethyl acetate

water

Conditions

Workup

1. 1
   Temperatureby refluxing
2. 2
   FiltrationAfter filtration
3. 3
   Otherthe organic layer was separated
4. 4
   Concentrationwas subjected to vacuum concentration

Procedure

Chloroacetaldehyde diethyl acetal (2.00 g), benzoic acid (2.16 g), potassium iodide (0.27 g), potassium carbonate (1.11 g) and DMF (20 mL) were placed in a three-neck flask, followed by refluxing. Twenty hours later, the reaction mixture was cooled to room temperature, and water (30 mL) and ethyl acetate (80 mL) were added thereto, followed by stirring. After filtration, the organic layer was separated, was subjected to vacuum concentration and thereby yielded the target compound (1.74 g) in a yield of 56%.

Source