Reaction #417924

Reaction equation

sodium hydroxide

29

methyl 2-(undec-4Z-enyloxy)benzoate

→

yellow oil

Yield 99.5%

2-(undec-4Z-enyloxy)benzoic acid

Yield 99.5%

Solvents

methanol

Conditions

Workup

1. 1
   TemperatureThe solution is refluxed for 24 hours
2. 2
   OtherAfter evaporating off the solvent
3. 3
   Extractionextracted with DCM

Procedure

500 μL of 1 N sodium hydroxide solution (500 μmol) are added portionwise to 80 mg of 29 (263 μmol) in methanol (3 mL). The solution is refluxed for 24 hours. After evaporating off the solvent, the reaction medium is acidified with 0.5 N HCl and extracted with DCM. 76 mg of a yellow oil are obtained, i.e. a yield of 99%.

Source