Reaction #41598

Reaction equation

4-(2-chloropyridin-3-yloxy)-5-(6-ethanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine

5-(2-Chloropyridin-3-yloxy)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-pyridin-2-yl-1H-benzimidazole

1-methyl-1H-pyrazole-3-carboxylic acid

→

5-(2-Chloropyridin-3-yloxy)-2-(1-methyl-1H-pyrazol-3-yl)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-1H-benzimidazole

Conditions

Workup

1. 1
   OtherThe entitled compound was obtained as a colorless solid in the same method as in Example 203 or in accordance with the method

Procedure

The entitled compound was obtained as a colorless solid in the same method as in Example 203 or in accordance with the method or by combining it with an ordinary method but using 4-(2-chloropyridin-3-yloxy)-5-(6-ethanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine obtained in Example 242 and 1-methyl-1H-pyrazole-3-carboxylic acid.

Source