Reaction #41597

Reaction equation

4-(2-chloropyridin-3-yloxy)-5-(6-ethanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine

5-(2-Chloropyridin-3-yloxy)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-pyridin-2-yl-1H-benzimidazole

pyrazine-2-carboxylic acid

→

5-(2-Chloropyridin-3-yloxy)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-pyrazin-2-yl-1H-benzimidazole

Conditions

Workup

1. 1
   OtherThe entitled compound was obtained as a colorless solid in the same method as in Example 197 or in accordance with the method

Procedure

The entitled compound was obtained as a colorless solid in the same method as in Example 197 or in accordance with the method or by combining it with an ordinary method but using 4-(2-chloropyridin-3-yloxy)-5-(6-ethanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine obtained in Example 242 and pyrazine-2-carboxylic acid.

Source