Reaction #40855
ord-6657e0aca0cb44d894f6e71979dee592
Reaction equation
1-phenyl-2-p-tolylethanone
dimethylformamide dimethylacetal
→
title compound
(E)-3-(Dimethylamino)-1-phenyl-2-p-tolylprop-2-en-1-one
Reagents
None
Solvents
Conditions
Detailed conditions
See reaction.notes.procedure_details.
Workup
- 1OtherSolvents were removed under high vacuum
Procedure
A solution of 1-phenyl-2-p-tolylethanone (2 g, 9.5 mmol) and dimethylformamide dimethylacetal (4.5 g, 38.1 mmol) in DMF (30 ml) was heated at 75° C. for 24 hours. Solvents were removed under high vacuum to obtain the title compound as a yellow oil, which was used directly in the next step without purification.