Reaction #40586

ord-547db05fcb5b4d15ad1859b271b0aa20

Reaction equation

Cc1ccc(N)c(Br)n1
3-amino-2-bromo-6-methylpyridine
O=S(=O)(Cl)c1ccc2ncsc2c1
6-benzothiazolesulfonyl chloride
→
Cc1ccc(NS(=O)(=O)c2ccc3ncsc3c2)c(Br)n1
expected product
Yield 35.0%
Cc1ccc(NS(=O)(=O)c2ccc3ncsc3c2)c(Br)n1
N-(2-Bromo-6-methyl-3-pyridyl)-6-benzothiazolesulfonamide
Yield 35.0%

Reactants

—
VII
Cc1ccc(N)c(Br)n1
3-amino-2-bromo-6-methylpyridine
O=S(=O)(Cl)c1ccc2ncsc2c1
6-benzothiazolesulfonyl chloride

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

By working in a manner similar to that of Preparation VII, starting with 3-amino-2-bromo-6-methylpyridine and 6-benzothiazolesulfonyl chloride, the expected product is obtained in the form of a beige-colored paste (yield=35%).

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07728002B2uspto-grants-2010_06