Reaction #4056

Reaction equation

phenyl diphenylphosphinate

sodium trimethylsilanolate

→

Sodium diphenylphosphinate

Yield 68.0%

Solvents

tetrahydrofuran

Conditions

Workup

1. 1
   workup.WAITwas left

Procedure

The procedure of Example 1 was followed except that a mixture of phenyl diphenylphosphinate (13.76 g, 46.7 mmol), sodium trimethylsilanolate (5.6 g, 50 mmol), and dry tetrahydrofuran (175 mL) was left standing overnight (as it became impossible to stir). Sodium diphenylphosphinate (7.6 g, 68% yield) was isolated as a white solid: 1H NMR (D2O) δ 6.6-8.0 (m, Ar--H's 10H). Anal. Calcd. for C12H10NaO2P: C, 60.01; H, 4.20; P, 12.90. Found: C, 55.25, 55.47; H, 4.22, 4.20; P, 11.06, 11.15.

Source