Reaction #4053

Reaction equation

diethylfluorophosphate

potassium trimethylsilanolate

→

Potassium diethylphosphate

Yield 54.5%

Solvents

ether

Conditions

Workup

1. 1
   Otherreaction time

Procedure

The procedure of Example 1 was followed except that diethylfluorophosphate (0.9 mL, 6.4 mmol) was added by syringe to a slurry of potassium trimethylsilanolate (0.82 g, 6.4 mmol) in dry ether (25 mL) and a 5 h reaction time was used. Potassium diethylphosphate (0.67 g, 54% yield) was isolated as a tan solid: 1H NMR (D2O, DSS) δ 1.2 (t, J=6.9 Hz, CH3, 6H), 3.9 (q, J=6.9 Hz, CH2, 4H).

Source