Reaction #4043

Reaction equation

perfluoro-2-methyl-3-oxahexanoyl fluoride

potassium trimethylsilanolate

→

Potassium perfluoro-2-methyl-3-oxahexanoate

Yield 72.0%

Solvents

ether

Conditions

Workup

1. 1
   ConcentrationPotassium perfluoro-2-methyl-3-oxahexanoate (12.3 g initially and 0.9 g by concentrating the filtrate under vacuum
2. 2
   Othertotal: 13.2 g, 72% yield) was isolated as a white solid

Procedure

The procedure of Example 1 was followed using perfluoro-2-methyl-3-oxahexanoyl fluoride (16.6 g, 50 mmol), potassium trimethylsilanolate (6.41 g, 50 mmol), and dry ether (300 mL). Potassium perfluoro-2-methyl-3-oxahexanoate (12.3 g initially and 0.9 g by concentrating the filtrate under vacuum; total: 13.2 g, 72% yield) was isolated as a white solid: 19F NMR (D2O) δ -81.0 ##STR12##

Source