Reaction #40318

ord-b69ffd70b70b453990f6ee758973e6dd

Reaction equation

CCOC(=O)C1CCCC(Br)C1=O
3-bromo-2-oxo-cyclohexane carboxylic acid ethyl ester
NC(=S)N=C(N)N
2-imino-4-thiobiuret
→
CCOC(=O)C1CCCc2sc(NC(=N)N)nc21
title compound
CCOC(=O)C1CCCc2sc(NC(=N)N)nc21
2-guanidino-4,5,6,7-tetrahydro-benzothiazole-4-carboxylic acid ethyl ester

Reactants

CCOC(=O)C1CCCC(Br)C1=O
3-bromo-2-oxo-cyclohexane carboxylic acid ethyl ester
NC(=S)N=C(N)N
2-imino-4-thiobiuret

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

Analogously to the preparation of Example C-01, 3-bromo-2-oxo-cyclohexane carboxylic acid ethyl ester is reacted with 2-imino-4-thiobiuret to produce the title compound.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07727979B2uspto-grants-2010_06