Reaction #362457

ord-b05fdaa66b7647419f3796a578d6dd6a

Reaction equation

C[Si](C)(C)[O-].[Na+]
sodium trimethylsilanolate
[Br-].[Br-].[Zn+2]
zinc bromide
→
C[Si](C)(C)[O-].C[Si](C)(C)[O-].[Zn+2]
Zinc trimethylsilanolate

Reactants

C[Si](C)(C)[O-].[Na+]
sodium trimethylsilanolate
—
solution
[Br-].[Br-].[Zn+2]
zinc bromide
—
solution

Reagents

None

Solvents

C1CCOC1
tetrahydrofuran
C1CCOC1
tetrahydrofuran

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    workup.ADDITIONTo this solution were added
  2. 2
    Otherto warmup to ambient temperature
  3. 3
    workup.STIRRINGwas stirred overnight
  4. 4
    FiltrationThe mixture was filtered

Procedure

100 cm3 of a 0.5 M solution of zinc bromide in dry tetrahydrofuran were cooled to 0° C. and stirred under argon. To this solution were added, dropwise, 100 cm3 of a 1 M solution of sodium trimethylsilanolate in dry tetrahydrofuran. The mixture was allowed to warmup to ambient temperature and was stirred overnight. The mixture was filtered. The filtrate was used as a 0.25 M solution of zinc trimethylsilanolate in tetrahydrofuran.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05393750uspto-grants-1995_02