Reaction #355753

ord-3be9e6a1ff784fccb293c9e66a4165de

Reaction equation

Brc1ccc2c(c1)Cc1ccccc1-2
2-bromofluorene
CC(=O)OC(C)=O.O=[N+]([O-])c1ccccc1.[Al+3].[Cl-].[Cl-].[Cl-]
acetic anhydride AlCl3 nitrobenzene
→
CC(=O)c1ccc2c(c1)Cc1cc(Br)ccc1-2
1-(7-bromo-9H-fluoren-2-yl)-ethanone

Reactants

Brc1ccc2c(c1)Cc1ccccc1-2
2-bromofluorene
CC(=O)OC(C)=O.O=[N+]([O-])c1ccccc1.[Al+3].[Cl-].[Cl-].[Cl-]
acetic anhydride AlCl3 nitrobenzene

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

1-(7-bromo-9H-fluoren-2-yl)-ethanone is prepared by the reaction of 2-bromofluorene (available from Aldrich Chemical Company, Milwaukee, Wis.) with acetic anhydride/AlCl3/nitrobenzene according to Tsuno et al., Bull. Chem. Soc. Jpn., 51, 601-607 (1978), incorporated herein by reference.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07445825B2uspto-grants-2008_11