Reaction #351306

Reaction equation

tridecanoic acid, methyl ester

hydrazine

→

Tridecanoic acid hydrazide

Solvents

ethanol

Conditions

Workup

1. 1
   Temperaturerefluxed 2 days
2. 2
   Temperatureto cool
3. 3
   Otherthe solid that crystallized
4. 4
   Filtrationwas filtered off
5. 5
   Washwashed
6. 6
   Otherdried in vacuo

Procedure

A solution of tridecanoic acid, methyl ester (24.63 g, 0.1078 mol), and anhydrous hydrazine (3.40 mL, 0.108 mol) in absolute ethanol (150 mL) was stirred at room temperature for 24 hours, then refluxed 2 days. The solution was allowed to cool, and the solid that crystallized was filtered off, washed, and dried in vacuo; yield 18.6 g (75%); mp 101°-104° C.

Source