Reaction #346292

ord-39c5f9257de1457b8f05a27888ecf82a

Reaction equation

N#Cc1c([N+](=O)[O-])cccc1[N+](=O)[O-]
2,6-dinitrobenzonitrile
CS
methylmercaptan
CSc1cccc([N+](=O)[O-])c1C#N
2-(methylthio)-6-nitrobenzonitrile
→
CSc1cccc(N)c1C(N)=O
2-Amino-6-(methylthio) benzamide

Reactants

N#Cc1c([N+](=O)[O-])cccc1[N+](=O)[O-]
2,6-dinitrobenzonitrile
CS
methylmercaptan
CSc1cccc([N+](=O)[O-])c1C#N
2-(methylthio)-6-nitrobenzonitrile

Reagents

[Ni]
Raney nickel

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

2-Amino-6-(methylthio) benzamide is prepared by Raney nickel reduction of 2-(methylthio)-6-nitrobenzonitrile which is prepared from 2,6-dinitrobenzonitrile and methylmercaptan following the procedure set forth in Example 75.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04036837uspto-grants-1977_07