Reaction #346291

ord-2f6f0c5ff1b84278ac4f04f9b66b3eec

Reaction equation

N#Cc1c([N+](=O)[O-])cccc1[N+](=O)[O-]
2,6-dinitrobenzonitrile
CNC.Cl
dimethylamine hydrochloride
[K+].[OH-]
KOH
CN(C)C=O
dimethylformamide
→
CN(C)c1cccc([N+](=O)[O-])c1C#N
2-Dimethylamino-6-nitrobenzonitrile

Reactants

N#Cc1c([N+](=O)[O-])cccc1[N+](=O)[O-]
2,6-dinitrobenzonitrile
CNC.Cl
dimethylamine hydrochloride
[K+].[OH-]
KOH
CN(C)C=O
dimethylformamide

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

2-Dimethylamino-6-nitrobenzonitrile is prepared from molar equivalents of 2,6-dinitrobenzonitrile and dimethylamine hydrochloride in dimethylformamide in the presence of aqueous KOH.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04036837uspto-grants-1977_07