Reaction #336863

ord-f9e7f93711a649caa20e9b90672a7411

Reaction equation

CCOC(=O)c1c(C)nc2ccccc2c1Cl
3g
CCOC(=O)c1c(C)nc2ccccc2c1Cl
Ethyl 4-chloro-2-methyl-quinoline-3-carboxylate
NNc1ccccc1
phenyl hydrazine
Cc1[nH]c2ccccc2c2nn(-c3ccccc3)c(=O)c1-2
title compound
Cc1[nH]c2ccccc2c2nn(-c3ccccc3)c(=O)c1-2
4-Methyl-2-phenyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-3-one

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

The title compound was synthesized following the procedure described in step 3 using 3g and phenyl hydrazine. 1H NMR (DMSO-d6) δ (ppm): 2.77 (3H, s), 7.13 (1H, t, J=7.42 Hz), 7.45 (3H, m), 7.62 (2H, m), 8.20 (3H, m). m/z 276.4 (MH+).

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07863266B2uspto-grants-2011_01