Reaction #336859
ord-d1d780ae30f24fec9ae1d8c93ea47bf8
Reaction equation
4a
2-Phenyl-2,5-dihydro-pyrazolo-(4,3-c) quinolin-3-one
3c
Ethyl 4-chloro-6,7-difluoro-quinoline-3-carboxylate
phenyl hydrazine
→
title compound
7,8-Difluoro-2-phenyl-2,5-dihydro-pyrazolo-(4,3-c)quinolin-3-one
Reactants
Reagents
None
Conditions
Detailed conditions
See reaction.notes.procedure_details.
Procedure
The title compound was prepared following the procedure described in Step 3 for the synthesis of 4a, using 3c and phenyl hydrazine. 1H NMR (DMSO-d6) δ (ppm): 7.18 (1H, t, J=7.82 Hz), 7.43 (2H, dd, J=8.30, 7.33 Hz), 7.75 (1H, dd, J=11.22, 7.32 Hz), 8.18, 3H, m), 8.90 (1H, s). m/z 298.2 (MH+).