Reaction #336826

ord-7139a240634c497580c7cc601ec346c1

Reaction equation

CCCCCCCCCCCCO
1-dodecanol
CCOC(=O)C(C)O
ethyl lactate
CCCCCCCCCCCCOC(=O)C(C)O
lauryl lactate
Yield 80.0%

Reagents

None

Conditions

Temperature
60°CELSIUS
Detailed conditions
See reaction.notes.procedure_details.

Procedure

A mixture of Novozym® 435 (500 g), 1-dodecanol (2000 mL), and ethyl lactate (2000 mL) in a 5 L reactor was stirred (˜200 rpm) at 60±5° C. for 28 hours. Upon work-up, 2000 g of lauryl lactate (>80% yield) was obtained as a pale yellow liquid. The purity of the product was >95% as assessed by GC-FID.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07863025B2uspto-grants-2011_01