Reaction #336824

ord-cf7fa60b63d34f1b96960bec167f373f

Reaction equation

CCCCCCCCCCCCO
1-dodecanol
CCOC(=O)C(C)O
ethyl lactate
CCCCCCCCCCCCOC(=O)C(C)O
lauryl lactate
Yield 80.0%

Reagents

None

Conditions

Temperature
60°CELSIUS
Detailed conditions
See reaction.notes.procedure_details.

Procedure

A mixture of Novozym® 435 (1 kg), 1-dodecanol (2000 mL), and ethyl lactate (2000 mL) in a 50 L reactor was stirred (˜200 rpm) at 60±5° C. for 28 hours. Upon work-up, 2000 g of lauryl lactate (80% yield) was obtained as a pale yellow liquid. The purity of the product was >97% as assessed by GC.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07863025B2uspto-grants-2011_01