Reaction #321602

ord-849397e6d9df448c9aa893e77a75d277

Reaction equation

COc1ccccc1B(O)O
2-methoxyphenylboronic acid
O=S(=O)(c1ccc(Br)s1)n1cccc1
N-(5-bromothiophenesulfonyl)pyrrole
→
COc1ccccc1-c1ccc(S(=O)(=O)n2cccc2)s1
N-[5-(2-methoxyphenyl)thiophene-2-sulfonyl]pyrrole
Yield 74.0%

Reactants

COc1ccccc1B(O)O
2-methoxyphenylboronic acid
O=S(=O)(c1ccc(Br)s1)n1cccc1
N-(5-bromothiophenesulfonyl)pyrrole

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

N-[5-(2-methoxyphenyl)thiophene-2-sulfonyl]pyrrole was prepared in the same manner as described in Example 32C using 2-methoxyphenylboronic acid and N-(5-bromothiophenesulfonyl)pyrrole, 74% yield.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05594021uspto-grants-1997_01