Reaction #310954

Reaction equation

2-(2-pyridyl)imidazole

1,2-epoxydodecane

→

1-(2-hydroxydodecyl)-2-(2-pyridyl)imidazole

Conditions

Workup

1. 1
   Temperaturewas heated
2. 2
   ExtractionThe resulting product was then extracted with hot hexane
3. 3
   Othercollected as yellow crystals which

Procedure

A mixture of 14.5 g (0.1 mole) 2-(2-pyridyl)imidazole, 18.4 g (0.1 mole) 1,2-epoxydodecane and 3 drops of water was heated with stirring at about 160° C. under nitrogen for about one hour. The resulting product was then extracted with hot hexane and collected as yellow crystals which had a melting point of 62°-65° C.

Source