Reaction #308530

ord-a3583c59ca884dd2bdbdc000661bf0cd

Reaction equation

NNC(=O)c1ccncc1
Isonicotinic acid hydrazide
CCCCCC1CCC(C(=O)O)CC1
4-pentylcyclohexane carboxylic acid
→
CCCCC[C@H]1CC[C@H](C(=O)NNC(=O)c2ccncc2)CC1
title compound
CCCCC[C@H]1CC[C@H](C(=O)NNC(=O)c2ccncc2)CC1
trans 4 Pentyl-cyclohexanecarboxylic acid N′-(pyridine-4-carbonyl)hydrazide

Reactants

NNC(=O)c1ccncc1
Isonicotinic acid hydrazide
CCCCCC1CCC(C(=O)O)CC1
4-pentylcyclohexane carboxylic acid

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    Otherthat described in Preparation 16

Procedure

Isonicotinic acid hydrazide was reacted with 4-pentylcyclohexane carboxylic acid in a similar fashion to that described in Preparation 16 to afford the title compound: RT=4.79 min; m/z (ES+)=318.0 [M+H]+.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08207147B2uspto-grants-2012_06