Reaction #3063
ord-d5a686fbf7b9481c9a917b96b78bc8ab
Reaction equation
Reagents
None
Conditions
Detailed conditions
See reaction.notes.procedure_details.
Procedure
A solution of 1.0 mmol of 3-iodo-4-methylbenzoic acid, 1.2 mmol of TsCl, and 25 mmol of Py was stirred for 3 h and then 5 mmol of methylamine hydrochloride was added and stirring continued for 5 h. Chromatography provided N-methyl-(3-iodo-4-methylphenyl)carboxamide.