Reaction #2895

ord-24c2c46a829e48159acfde789ed8bd92

Reaction equation

CON(C)C(=O)c1oc(C)nc1C
N-methoxy-N-methyl-2,4-dimethyl-5-oxazolecarboxamide
[Li][C](C)(C)C
t-butyllithium
→
Cc1nc(C)c(C(=O)C(C)(C)C)o1
title compound
Cc1nc(C)c(C(=O)C(C)(C)C)o1
t-Butyl 2,4-Dimethyl-5-oxazolyl Ketone

Reactants

CON(C)C(=O)c1oc(C)nc1C
N-methoxy-N-methyl-2,4-dimethyl-5-oxazolecarboxamide
[Li][C](C)(C)C
t-butyllithium

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    Otherthe general method of Preparation 3

Procedure

Starting with N-methoxy-N-methyl-2,4-dimethyl-5-oxazolecarboxamide and t-butyllithium and following the general method of Preparation 3, the title compound was prepared.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05731335uspto-grants-1998_03