Reaction #2519

Reaction equation

2,5-dimethoxyaniline

4-nitrobenzoic acid

→

title compound

Yield 77.2%

4-Nitro-N-(2,5-dimethoxyphenyl)benzamide

Yield 77.2%

Conditions

Procedure

Using 2,5-dimethoxyaniline (2.53 g, 16.5 mmol) and 4-nitrobenzoic acid (2.51 g, 15.0 mmol), the procedure of Reference Example 16 was repeated to obtain 3.50 g (77.2%) of the title compound in the form of orange needle crystals.

Source