Reaction #2446120

ord-a80b731756c6451eb8ea3cc06d08d764

Reaction equation

C[C@]1(Cn2ccnn2)[C@H](C(=O)O)N2C(=O)C[C@H]2S1(=O)=O
tazobactam acid
N=C(N)NCCC[C@H](N)C(=O)O
arginine
→
C[C@]1(Cn2ccnn2)[C@H](C(=O)O)N2C(=O)C[C@H]2S1(=O)=O.N=C(N)NCCC[C@H](N)C(=O)O
Tazobactam Arginine

Reactants

C[C@]1(Cn2ccnn2)[C@H](C(=O)O)N2C(=O)C[C@H]2S1(=O)=O
tazobactam acid
N=C(N)NCCC[C@H](N)C(=O)O
arginine

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

The 1H-NMR spectrum (FIG. 7) of polymorph Ia indicates a stoichiometry of 1:1 tazobactam acid:arginine.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08685957B1uspto-grants-2014_04