Reaction #2358563

Reaction equation

Anthraquinone-2,7-disulfonylchloride

4-tert-butylcyclohexanamine

triethyl amine

→

product ( 1-36 )

N2,N7-bis(4-tert-butylcyclohexyl)-9,10-dioxo-9,10-dihydroanthracene-2,7-disulfonamide

Solvents

DCM

Conditions

Workup

1. 1
   OtherSolvent was evaporated
2. 2
   workup.ADDITIONthe residue was treated with MeOH
3. 3
   Filtrationfiltered off
4. 4
   Otherdried

Procedure

Anthraquinone-2,7-disulfonylchloride (10 g, 24.7 mmol)) was dissolved in 200 mL DCM. The solution was cooled to −50° C. To this solution was added 4-tert-butylcyclohexanamine (8.43 g, 54 mmol), followed by triethyl amine (8.6 ml, 61:7 mmol). The reaction mixture was stirred at room temperature for 4 hrs. Solvent was evaporated and the residue was treated with MeOH, filtered off, and dried to obtain 15 g (95%) of the product (1-36) as yellow powder.

Source