Reaction #2358546

Reaction equation

nitroaniline

Bis-benzyloxy benzoic acid methyl ester

propionyl chloride

→

nitro-phenyl-propionamide

Bis-benzyloxy benzoic acid

Conditions

Workup

1. 1
   OtherIn another embodiment the compounds can be prepared

Procedure

In another embodiment the compounds can be prepared as shown in Scheme III. A nitroaniline (1) can be reacted with propionyl chloride to yield nitro-phenyl-propionamide (2). NaH can then be added to a solution of (2) in anhydrous THF followed by iodomethane to give pure product nitro-phenyl-N-methyl-propionamide (3).

Source