Reaction #2329032

Reaction equation

N-ethoxycarbonyl phthalimide

H2O

→

2-(2-Phthalimidoethylamino)ethanol

Conditions

Workup

1. 1
   Washthe solid product washed with methanol (40 ml)
2. 2
   OtherThe remaining white solid (Compound 14) was collected
3. 3
   Otherdried

Procedure

10.4 g (0.1 mol) of N,N-(2-hydroxyethyl),ethyl amine and 22 g (0.1 mol) of N-ethoxycarbonyl phthalimide were dissolved in 50 ml of H2O and stirred for 2 hours. The reaction mixture was lyophilized and the solid product washed with methanol (40 ml). The remaining white solid (Compound 14) was collected and dried.

Source