Reaction #2314282

ord-f7a2900f3ceb4afbb7ca027c24dcc3cd

Reaction equation

CC(C)=CCCC1=CCC(CC(=O)O)CC1
acid 2B
CC(C)=CCCC1=CCC(CC(=O)O)CC1
(4-(4-Methyl-3-pentenyl)-3-cyclohexenyl)acetic acid
O=C(Cl)C(=O)Cl
oxalyl chloride
→
CC(C)=CCCC1=CCC(CC(=O)Cl)CC1
(4-(4-Methyl-3-pentenyl)-3-cyclohexenyl)acetyl chloride

Reactants

CC(C)=CCCC1=CCC(CC(=O)O)CC1
acid 2B
CC(C)=CCCC1=CCC(CC(=O)O)CC1
(4-(4-Methyl-3-pentenyl)-3-cyclohexenyl)acetic acid
O=C(Cl)C(=O)Cl
oxalyl chloride

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    workup.ADDITIONTo a 100 mL flask containing a stirbar
  2. 2
    OtherResidual oxalyl chloride is removed in vacuo

Procedure

To a 100 mL flask containing a stirbar is added the acid 2B (R=4-Methyl-3-pentenyl) (10 g) and oxalyl chloride (8.3 mL). The reaction is stirred under a nitrogen atmosphere for one hour after gas evolution ceases. Residual oxalyl chloride is removed in vacuo.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06413448B1uspto-grants-2002_07