Reaction #2293178

Reaction equation

tert-Butyl 2-(tetrahydro-2H-pyran-4-yl)hydrazinecarboxylate

hydrogen chloride-ethyl acetate

→

title compound

tetrahydro-2H-pyran-4-ylhydrazine dihydrochloride

Conditions

Workup

1. 1
   Temperaturecooling
2. 2
   ConcentrationThe reaction mixture was concentrated under reduced pressure

Procedure

tert-Butyl 2-(tetrahydro-2H-pyran-4-yl)hydrazinecarboxylate (1.82 g) was dissolved in 4N hydrogen chloride-ethyl acetate solution (85 mL) under ice-cooling, and the solution was stirred overnight at room temperature. The reaction mixture was concentrated under reduced pressure to give the title compound (1.52 g).

Source