Reaction #2275731
ord-5a977e7a16424cbfb33a0b2ae9d53043
Reaction equation
N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide
5-bromo-1-(4-oxo-cyclohexyl)-1H-pyrimidin-2-one
→
title compounds
N-({1-[4-(5-Bromo-2-oxo-2H-pyrimidin-1-yl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-3-trifluoromethyl-benzamide
Reactants
Reagents
None
Conditions
Detailed conditions
See reaction.notes.procedure_details.
Procedure
The title compounds were prepared as white solids from the reductive amination of 5-bromo-1-(4-oxo-cyclohexyl)-1H-pyrimidin-2-one (as prepared in the previous step) and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide (as prepared in Example 2 Step C) using the procedure described in Step D of Example 1.