Reaction #2200579

ord-1c63baaa7b784e589ea1319894e1fcf4

Reaction equation

CCOC(=O)CC(O)CCl
ethyl 4-chloro-3-hydroxybutyrate
C[Si](C)Cl
DMCS
→
CCOC(=O)CC(=O)CCl
Ethyl 4-Chloroacetoacetate

Reactants

CCOC(=O)CC(O)CCl
ethyl 4-chloro-3-hydroxybutyrate
C[Si](C)Cl
DMCS

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    Otherwas carried out at 150° C

Procedure

The quantitation of ethyl 4-chloro-3-hydroxybutyrate was carried out by gas chromatography. Thus, using a glass column (ID 3 mm×1 m) packed with PEG-20M Chromosorb WAW DMCS 10%, 80/100 mesh (product of GL Sciences Inc.), chromatography was carried out at 150° C. The detection was made by FID.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07432095B2uspto-grants-2008_10