Reaction #2171028

Reaction equation

1,3-bis-(3,5-dibromo-4-nitropyrazol-1-yl-methyl)benzene

benzylamine

water

→

1,3-bis-(5-benzylamino-3-bromo-4-nitropyrazol-1-yl-methyl)-benzene

Solvents

n-propanol

Conditions

Workup

1. 1
   TemperatureSubsequently the reaction mixture is cooled
2. 2
   FiltrationThe precipitate is filtered with suction

Procedure

13.9 g of 1,3-bis-(3,5-dibromo-4-nitropyrazol-1-yl-methyl)benzene from step 4.1 are heated together with 6.5 g of benzylamine in 130 ml of n-propanol for 2 hours at 95° C. Subsequently the reaction mixture is cooled and poured into 400 ml water. The precipitate is filtered with suction and recyrstallized from 150 ml of acetonitrile.

Source