Reaction #2146758

ord-2675193b5f7a44d98c8c3768f48dfed9

Reaction equation

O.O=C(O)CC(O)(CC(=O)O)C(=O)O
citric acid monohydrate
O.O.O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Na+].[Na+].[Na+]
trisodium citrate dihydrate
O.O.O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Na+].[Na+].[Na+]
tri-sodium citrate dihydrate
→
O.O=C(O)CC(O)(CC(=O)O)C(=O)O
Citric acid monohydrate
O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-]
Citrate

Reactants

O.O=C(O)CC(O)(CC(=O)O)C(=O)O
citric acid monohydrate
O.O.O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Na+].[Na+].[Na+]
trisodium citrate dihydrate
O.O.O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Na+].[Na+].[Na+]
tri-sodium citrate dihydrate

Reagents

None

Solvents

O
water
O
water
O
water

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

Citric acid monohydrate (Mwt 211 g/mole) was prepared in deionised water at a concentration of 0.1 M. A solution of tri-sodium citrate dihydrate, 0.1 M, (Mwt 294.1 g/mole) was also prepared in deionised water. Citrate buffer solution pH 3 was prepared by mixing 40% v/v citric acid monohydrate solution (0.1 M), 10% v/v trisodium citrate dihydrate solution (0.1 M) and 50% v/v deionised water and the final pH was measured using a pH Meter (3320 JENWAY).

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08278292B2uspto-grants-2012_10