Reaction #214432

Reaction equation

1-(2-hydroxy-3-n-hexadecyloxypropyl)-piperizine

4-fluorobenzyl chloride

→

1-(4-fluorobenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine

Conditions

Procedure

Following the procedure of Example 5, 1-(2-hydroxy-3-n-hexadecyloxypropyl)-piperizine was reacted with 4-fluorobenzyl chloride to form 1-(4-fluorobenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine, mp 242° C. (dec).

Source