Reaction #214429

ord-cba2737f6dda4ea18c3edc6c3a02b8c9

Reaction equation

CCCCCCCCCCCCCCCCOCC(O)CN1CCNCC1
1-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine
ClCc1ccc(Cl)cc1
4-chlorobenzylchloride
→
CCCCCCCCCCCCCCCCOCC(O)CN1CCN(Cc2ccc(Cl)cc2)CC1
1-(4-chlorobenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine

Reactants

CCCCCCCCCCCCCCCCOCC(O)CN1CCNCC1
1-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine
ClCc1ccc(Cl)cc1
4-chlorobenzylchloride

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

Following the procedure of Example 5, 1-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine was reacted with 4-chlorobenzylchloride to form 1-(4-chlorobenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine, mp 237°-239° C.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04255426uspto-grants-1981_03