Reaction #2135

ord-6c4f2236d92e42d3ad896c3d86de7aab

Reaction equation

CCOP(=O)(CCCCCn1c(=O)c2[nH]cnc2n(C)c1=O)OCC
diethyl [5-(3-methyl-xanthin-1-yl)pentyl]phosphonate
ClCC1CC1
chloromethylcyclo-propane
→
CCOP(=O)(CCCCCn1c(=O)c2c(ncn2CC2CC2)n(C)c1=O)OCC
Diethyl [5-(7-cyclopropylmethyl-3-methylxanthin-1-yl)pentyl]phosphonate

Reactants

CCOP(=O)(CCCCCn1c(=O)c2[nH]cnc2n(C)c1=O)OCC
diethyl [5-(3-methyl-xanthin-1-yl)pentyl]phosphonate
ClCC1CC1
chloromethylcyclo-propane

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

The title substance was prepared from 0.011 mol of diethyl [5-(3-methyl-xanthin-1-yl)pentyl]phosphonate and 0.013 mol of chloromethylcyclo-propane analogously to Example 46.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05728686uspto-grants-1998_03