Reaction #2069941

Reaction equation

Thionyl chloride

4-n-butylbenzyl alcohol

→

title compound

Yield 104.9%

1-(Chloromethyl)-4-n-butylbenzene

Yield 104.9%

Solvents

ether

Conditions

Workup

1. 1
   OtherAfter concentration of the mixture, excess thionyl chloride was removed by azeotropic distillation with benzene

Procedure

Thionyl chloride (2.5 ml, 34 mmol) was added to a solution of 4-n-butylbenzyl alcohol (2.0 g, 12 mmol) in ether (25 ml), and this mixture was stirred at room temperature for 3 hours. After concentration of the mixture, excess thionyl chloride was removed by azeotropic distillation with benzene to give the title compound (2.3 g). This compound was used in the following reaction without purification.

Source