Reaction #1973965

Reaction equation

4-chloro-3-nitroaniline

methanesulfonyl chloride

pyridine

→

title compound

Yield 92.2%

N-(4-chloro-3-nitrophenyl)methanesulfonamide

Yield 92.2%

Solvents

THF

HCl

Conditions

Workup

1. 1
   FiltrationThe resulting precipitate was filtered
2. 2
   Otherair-dried

Procedure

A mixture of 4-chloro-3-nitroaniline (5.0 g, 29 mmol), methanesulfonyl chloride (2.37 mL, 30.4 mmol) and pyridine (5.9 mL, 72.4 mmol) in THF (100 mL) was stirred for 24 h. Poured in 1M HCl (500 mL). The resulting precipitate was filtered and air-dried to provide the title compound as a solid (6.7 g, 92%).

Source