Reaction #1973950

ord-fa8b2da9e62f41dda81297dcad4f1235

Reaction equation

CN1CCCC1=O
NMP
CN1CCCC1=O
NMP
CN1CCCN(C)C1=O
DMPU
OC[C@H]1O[C@@H](Oc2c[nH]c3ccc(Br)c(Cl)c23)[C@H](O)[C@@H](O)[C@H]1O
X-gal
CN1CCCN(C)C1=O
DMPU
→
CN1CCCC1=O.CO
NMP Methanol

Reactants

CN1CCCC1=O
NMP
CN1CCCC1=O
NMP
CN1CCCN(C)C1=O
DMPU
OC[C@H]1O[C@@H](Oc2c[nH]c3ccc(Br)c(Cl)c23)[C@H](O)[C@@H](O)[C@H]1O
X-gal
CN1CCCN(C)C1=O
DMPU

Reagents

None

Solvents

CO
methanol

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    workup.DISSOLUTIONuntil dissolved
  2. 2
    workup.ADDITIONmix thoroughly

Procedure

Add 7 ml of either NMP or DMPU to 1 gram of X-gal and stir until dissolved. Bring to 10 ml with NMP or DMPU (whichever is already used). Add 90 ml of methanol and mix thoroughly.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08501433B2uspto-grants-2013_08