Reaction #1960

Reaction equation

product

4-Chloro-5-fluoro-2-propyl-pyridine

4-chloro-5-fluoro-2-picoline

product

4-Chloro-5-fluoro-2-picoline

4-chloro-5-fluoro-2-propyl-pyridine

→

title compound

4-Chloro-3,5-difluoro-2-propyl-pyridine

Conditions

Procedure

By following the procedures described in Example 69 and replacing 4-chloro-5-fluoro-2-picoline (the product of Example 66) with 4-chloro-5-fluoro-2-propyl-pyridine (the product of Example 70), the title compound can be prepared.

Source