Reaction #1929051

ord-e1c48d6ba812406c9fb07921d79de211

Reaction equation

CCC(O)CCCCCCCCCCCCCCC(=O)O
16-hydroxystearic acid
CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21
Dess-Martin reagent
→
CCC(=O)CCCCCCCCCCCCCCC(=O)O
16-oxostearic acid

Reactants

CCC(O)CCCCCCCCCCCCCCC(=O)O
16-hydroxystearic acid
CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21
Dess-Martin reagent

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

16-hydroxystearic acid was selectively oxidized with Dess-Martin reagent to yield 16-oxostearic acid. The crude product was purified by chromatography using silica gel as separating agent.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08945897B2uspto-grants-2015_02