Reaction #1810830

ord-b3168982d8dc4e12b12d7ed750d9ec29

Reaction equation

CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O
2-isopropoxy-5-methanesulfonyl-benzoic acid
CS(=O)(=O)c1ccc(C2=CCNCC2)cc1
4-(4-Methanesulfonyl-phenyl)-1,2,3,6-tetrahydro-pyridine
→
CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CC=C(c2ccc(S(C)(=O)=O)cc2)CC1
title compound
CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CC=C(c2ccc(S(C)(=O)=O)cc2)CC1
(2-Isopropoxy-5-methanesulfonyl-phenyl)-[4-(4-methanesulfonyl-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-methanone

Reactants

CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O
2-isopropoxy-5-methanesulfonyl-benzoic acid
CS(=O)(=O)c1ccc(C2=CCNCC2)cc1
4-(4-Methanesulfonyl-phenyl)-1,2,3,6-tetrahydro-pyridine

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    Otherdescribed for the synthesis of example 4, step f

Procedure

According to the procedure described for the synthesis of example 4, step f, the title compound has been synthesized 2-isopropoxy-5-methanesulfonyl-benzoic acid and 4-(4-Methanesulfonyl-phenyl)-1,2,3,6-tetrahydro-pyridine. MS (m/e): 495.4 (M+NH4+, 100%)

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07485637B2uspto-grants-2009_02