Reaction #1797482

Reaction equation

phthalic acid

KOH

→

Monoisobutylphthalic Acid

Solvents

isobutyl alcohol

Conditions

Workup

1. 1
   Otherequipped with stirring blades
2. 2
   Temperaturethermometer and Dimroth condenser, heated
3. 3
   Temperatureraised to a temperature of 140° C., which
4. 4
   Temperaturewas maintained for 2 hours
5. 5
   TemperatureThe mixture was subsequently cooled to 60° C

Procedure

148.2 g of anhydrous phthalic acid and the molar equivalent 74.2 g of isobutyl alcohol were added to a 500 ml glass round-bottomed flask equipped with stirring blades, thermometer and Dimroth condenser, heated while slowly stirring, and after the generated heat at about 80° C. wore off, raised to a temperature of 140° C., which was maintained for 2 hours. The mixture was subsequently cooled to 60° C. The acid value (number of mg of KOH necessary to neutralize 1 g of a sample) of the reaction solution was 257.5. Since the acid value for the case where the reaction is 100% complete is 252.4, the reaction rate was computed to be 98%.

Source