Reaction #1790931

Reaction equation

1,1-dimethylethanolamine

4-n-nonylcyclohexanone

toluene

→

desired product

3,3-Dimethyl-8-Nonyl-1-Oxa-4-Azaspiro[4.5]Decane

Conditions

Workup

1. 1
   OtherAfter removing the toluene
2. 2
   workup.DISTILLATIONthe residue was distilled

Procedure

The procedure of Example 1 was followed utilizing 1,1-dimethylethanolamine (2.7 grams; 0.03 mole) and 4-n-nonylcyclohexanone (6.73 grams; 0.03 mole) in 100 mls of toluene. After removing the toluene, the residue was distilled to obtain 4.3 grams (48.5% of theoretical; b.p. 113°-115° C. at 0.01 mm.) of the desired product.

Source