Reaction #1788964

Reaction equation

( a )

4,13-Diaminohexadecane

3,12-dipropyl-1,2-diaza-1,5,9-cyclododecatriene

3,12-dicycloheptyl-1,2-diaza-1,5,9-cyclododecatriene

→

1,10-Diamino-1,10-dicycloheptyldecane

Conditions

Workup

1. 1
   Otherwith otherwise the same procedure, there is obtained
2. 2
   Otherafter chromatographic purification, and 63 g (58% of theory) of 1,10-diamino-1,10-dicycloheptyldecane as colourless oil [nD20 =1.5018; IR (liquid) inter alia bands at 3390, 3310 and 3618 cm-1 ]

Procedure

If there are used in the manner described under (a), instead of 942 g (3.79 mols) of 3,12-dipropyl-1,2-diaza-1,5,9-cyclododecatriene, 106 g (0.3 mol) of 3,12-dicycloheptyl-1,2-diaza-1,5,9-cyclododecatriene (diastereoisomeric mixture) and correspondingly reduced amounts of catalyst and solvent, with otherwise the same procedure, there is obtained, after chromatographic purification, and 63 g (58% of theory) of 1,10-diamino-1,10-dicycloheptyldecane as colourless oil [nD20 =1.5018; IR (liquid) inter alia bands at 3390, 3310 and 3618 cm-1 ].

Source